GSE113943 The response of the hypothalamus to leptin and a high-fat diet in mice

Contributors : Lynda M Williams ; Claus-Dieter Mayer ; Michael Muller ; Baukje de Roos ; Eva-Maria BachmairSeries Type : Expression profiling by arrayOrganism : Mus musculusEnergy homeostasis is regulated by the hypothalamus but fails when animals are fed a high-fat diet (HFD), and leptin insensitivity and obesity develops. We have used a microarray-based transcriptomics approach to identify novel genes regulated by HFD and leptin in the hypothalamus using mouse global arrays.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Mus musculus Source Type: research