Microbiome 101: Studying, Analyzing, and Interpreting Gut Microbiome Data for Clinicians
Advances in technical capabilities for reading out complex human microbiomes are leading to an explosion of microbiome research, leading in turn to intense interest among clinicians in applying these techniques to their patients. In this review, we discuss the content of the human microbiome, including inter- and intra-subject variability, considerations of study design including important confounding factors, and different methods in the laboratory and on the computer to read out the microbiome and its resulting gene products and metabolites.
Source: Clinical Gastroenterology and Hepatology - Category: Gastroenterology Authors: Celeste Allaband, Daniel McDonald, Yoshiki V ázquez-Baeza, Jeremiah J. Minich, Anupriya Tripathi, David A. Brenner, Rohit Loomba, Larry Smarr, William J. Sandborn, Bernd Schnabl, Pieter Dorrestein, Amir Zarrinpar, Rob Knight Source Type: research