NRG1‐ErbB signalling promotes microglia activation contributing to incision‐induced mechanical allodynia

ConclusionIncision‐induced NRG1 expression mediated activation of dorsal horn microglia and contributed to the development of mechanical allodynia. Specifically targeting NRG1‐ErbB signalling may therefore provide a new therapeutic intervention for relieving incision‐induced mechanical allodynia.

Source: European Journal of Pain - August 27, 2014 Category: Anesthesiology Authors: Y. Xiang, T. Liu, H. Yang, F. Gao, H. Xiang, A. Manyande, Y. Tian, X. Tian Tags: Original Article Source Type: research