Efficacy and safety of tapentadol prolonged release formulation in the treatment of elderly patients with moderate to severe chronic osteoarthritis knee pain: a pooled analysis of two double-blind, randomized, placebo- and active-controlled trials.

CONCLUSIONS: Tapentadol PR was effective in the treatment of moderate to severe chronic OA pain in elderly and younger patients. Compared to oxycodone CR, the overall and the gastrointestinal tolerability profile in particular were better in all tapentadol PR groups regardless of age. PMID: 30200781 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research