Renal complications and subsequent mortality in acute critically ill patients without pre-existing renal disease.

Renal complications and subsequent mortality in acute critically ill patients without pre-existing renal disease. CMAJ. 2018 Sep 10;190(36):E1070-E1080 Authors: Huang ST, Ke TY, Chuang YW, Lin CL, Kao CH Abstract BACKGROUND: Most studies of long-term renal outcomes after acute critical illness have enrolled patients with pre-existing renal dysfunction. We assessed renal outcomes in patients who did not have pre-existing renal disease and who were admitted to hospital for acute critical illness. METHODS: We identified adults who did not have pre-existing renal disease and who were admitted to hospital for acute critical illness between 2000 and 2011, from the Taiwan National Health Insurance Research Database. Each patient was matched 1:2 with controls without acute critical illness, according to age, sex and index date. A subset was further matched 1:1 with controls using propensity scores. Outcomes included acute kidney injury, chronic kidney disease and end-stage renal disease. RESULTS: We evaluated 33 613 patients with acute critical illness matched to 63 148 controls, of whom 14 218 were propensity matched to 14 218 controls. Patients with acute critical illness had incidence rates per 10 000 person-years of 9.45 for acute kidney injury, 78.3 for chronic kidney disease and 21.0 for end-stage renal disease. In the propensity-matched cohort, patients with acute critical illness had significantly higher risks of acut...
Source: cmaj - Category: General Medicine Authors: Tags: CMAJ Source Type: research