Carcinome rénal à cellules chromophobes : à propos de 16 cas et une revue de la littérature

ConclusionLe cancer chromophobe du rein est une entité anatomoclinique particulière, caractérisé par un pronostic favorable grâce à un grade de Fuhrman bas et sa limitation au rein.AbstractObjectiveTo determine the histo-clinical, pathological, therapeutic and prognostic characteristics of renal chromophobe carcinomas.Subjects and methodsThis is a retrospective study including 16 cases of chromophobe carcinoma among 86 renal cancers diagnosed in the Urology Department B of Rabat University Hospital between January 2011 and August 2017.ResultsThere were 12 women and 4 men. The average age of discovery was 57.5 years. They were distributed in 62.5% predominantly eosinophilic, 37.5% of mixed tumors. The nuclei are irregular and incisured. Tumor T1 (31.5%) and T2 (56.25%) were the most common. The majority of patients had a Fuhrman grade, 43.8% grade 2 and 31.2% grade 3. Only one patient had a local recurrence. The overall 5-year survival rate was 92%. A death related to the disease has been reported. Nephrectomy is the gold standard for 100% of patients. The average overall survival rate is 34.4 months.ConclusionChromophobic kidney cancer is a particular anatomo-clinical entity, characterized by a favorable prognosis due to a low Fuhrman grade and its limitation to the kidney.
Source: African Journal of Urology - Category: Urology & Nephrology Source Type: research