Modulatory role of the intra-accumbal CB1 receptor in protein level of the c-fos and pCREB/CREB ratio in the nucleus accumbens and ventral tegmental area in extinction and morphine seeking in the rats.

In conclusion, the results presented here provide compelling evidence of the modulation and involvement of the c-fos and the CREB molecules in the cannabinoid-opioid interaction of the brain reward system in the CPP paradigm. PMID: 30170186 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30170186?dopt=Abstract

Source: Brain Research Bulletin - August 28, 2018 Category: Neurology Authors: Khaleghzadeh-Ahangar H, Khodagholi F, Shaerzadeh F, Haghparast A Tags: Brain Res Bull Source Type: research

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