Copper Oxide Nanoparticles Induces Oxidative Stress and Liver toxicity in Rats following Oral Exposure

Publication date: Available online 31 August 2018Source: Toxicology ReportsAuthor(s): Anreddy Rama Narsimha ReddyAbstractThe present study aimed to evaluate the effect of Copper Oxide (CuO) Nanoparticles (NP) on liver following oral exposure in rats. A total of 18 male wister rats were used in the experiments including a control group (6 rats). NP were given to the rats with a doses (5, 50 mg/kg b.w./day) via oral gavage and a control group (received only 200 μl PBS). The treatment was continued for 14 days. The supernatants of rat Liver tissue homogenates were used to analyze for glutathione levels (GSH), Catalase, superoxide dismutase (SOD), the extent of lipid peroxidation products (Malondialdehyde, MDA). Oral administration of NP to rats caused a significant (P 
Source: Toxicology Reports - Category: Toxicology Source Type: research

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Source: International Journal of Sports Physiology and Performance - Category: Sports Medicine Tags: Int J Sports Physiol Perform Source Type: research
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