Super-early images of brain perfusion SPECT using 123 I-IMP for the assessment of hyperperfusion in stroke patients

AbstractObjectiveWith the advancement of reperfusion therapy in stroke patients, assessment of perfusion status after therapy is gaining importance. Hyperperfusion tends to be underestimated by the conventional early imaging of123I-IMP brain perfusion SPECT. We evaluated the utility of super-early imaging as an adjunct to early imaging for the assessment of postischemic hyperperfusion in stroke patients.MethodsSixty-seven patients who underwent123I-IMP brain perfusion SPECT within 14 days after the onset of cerebral infarction were retrospectively analyzed. Super-early (4 –10 min) and early (15–45 min) images were acquired using a dual-headed gamma camera. Postischemic hyperperfusion was visually assessed using the early images alone and then using both the super-early and early images, and the frequency of postischemic hyperperfusion and the confidence level o f the judgement were evaluated. For quantitative evaluation of image contrast, the contrast ratios (the count ratios of the hyperperfused to normal areas) were calculated.ResultsThe frequency of postischemic hyperperfusion was significantly higher using both the super-early and early images (28/67 patients) than using the early images alone (17/67 patients,p 
Source: Annals of Nuclear Medicine - Category: Nuclear Medicine Source Type: research

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Source: Journal of Musculoskeletal Neuronal Interactions - Category: Neurology Tags: J Musculoskelet Neuronal Interact Source Type: research
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Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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