Avascular necrosis of the femoral head in sickle cell disease in pediatric patients suffering from hip dysfunction.

CONCLUSIONS : Pediatric patients with sickle cell anemia with hip dysfunction present a prevalence of 39.4 % of osteonecrosis of the femoral head. This was associated with a longer time of diagnosis (97 months), previous trauma in 92 % of patients, and a mean Charnley score of 15 points. Also, an association with lower rate of fetal hemoglobin (7.2 versus 11.8) was found, which supports the hypothesis that fetal hemoglobin may function as a protective factor against avascular necrosis. PMID: 30137181 [PubMed]
Source: Revista de Salud Publica - Category: International Medicine & Public Health Tags: Rev Salud Publica (Bogota) Source Type: research