Efficacy of hypnosis on pain, wound-healing, anxiety, and stress in children with acute burn injuries: a randomized controlled trial

No randomized controlled trial has investigated the efficacy of hypnosis for reducing pain and improving wound-healing in children with burns. This randomized controlled trial aimed to investigate whether hypnosis decreases pain, anxiety, and stress and accelerates wound-healing in children undergoing burn wound procedures. Children (4-16 years) with acute burns presenting for their first dressing change were randomly assigned to a Hypnosis Group who received hypnosis plus standard care or a Standard Care Group who received standard pharmacological and nonpharmacological intervention. Repeated measures of pain intensity, anxiety, stress, and wound-healing were taken at dressing changes until ≥95% wound re-epithelialization. Data for 62 children were analyzed on an intent-to-treat basis using Generalized Estimating Equations (n = 35 Standard Care Group; n = 27 Hypnosis Group). An effect on the primary outcomes of pain and wound healing was not supported {self-reported pain intensity largest Mean Difference [MD] = −0.85 (95% confidence interval [CI]: −1.91 to 0.22), P = 0.12; MD for re-epithelialization = −0.46 [95% CI: −4.27 to 3.35], P = 0.81}. Some support was found for an effect on the secondary outcomes of preprocedural anxiety (MD = −0.80 [95% CI: −1.50 to −0.10], P = 0.03 before the second dressing change) and heart rate as a measure of stress (MD = −15.20 [−27.20 to −3.20], P = 0.01 and MD = −15.39 [−28.25 to −2.53], P = 0.02 before and after...
Source: Pain - Category: Anesthesiology Tags: Research Paper Source Type: research