The Natural History of Colorectal Polyps: Overview of Predictive Static and Dynamic Features.

The Natural History of Colorectal Polyps: Overview of Predictive Static and Dynamic Features.
Gastroenterol Clin North Am. 2018 Sep;47(3):515-536
Authors: Pickhardt PJ, Pooler BD, Kim DH, Hassan C, Matkowskyj KA, Halberg RB
Abstract
For decades, colorectal screening strategies have been largely driven by static features, particularly polyp size. Although cross-sectional features of polyp size, morphology, and location are important determinants of clinical relevance before histology, they lack any dynamic information on polyp growth rates. Computed tomography colonography allows for in vivo surveillance of colorectal polyps, providing volumetric growth rates that are providing new insights into tumorigenesis. In this article, existing cross-sectional and longitudinal data on colorectal polyps are reviewed, with an emphasis on how these features may affect clinical relevance and patient management.
PMID: 30115435 [PubMed - in process]

Source: Clinical Colorectal Cancer - August 19, 2018 Category: Cancer & Oncology Authors: Pickhardt PJ, Pooler BD, Kim DH, Hassan C, Matkowskyj KA, Halberg RB Tags: Gastroenterol Clin North Am Source Type: research