Upfront Gamma Knife radiosurgery for Cushing's disease and acromegaly: a multicenter, international study.

CONCLUSIONS Upfront GKS resulted in good tumor control as well as a low rate of adverse radiation effects in the whole group. Patients with CD achieved a faster and far better remission rate after upfront GKS in comparison to patients with acromegaly. GKS can be considered as an upfront treatment in carefully selected patients with CD who are unwilling or unable to undergo resection, but it has a more limited role in acromegaly.
PMID: 30117768 [PubMed - as supplied by publisher]

Source: Journal of Neurosurgery - August 17, 2018 Category: Neurosurgery Authors: Gupta A, Xu Z, Kano H, Sisterson N, Su YH, Krsek M, Nabeel AM, El-Shehaby A, Karim KA, Martínez-Moreno N, Mathieu D, McShane BJ, Martínez-Álvarez R, Reda WA, Liscak R, Lee CC, Lunsford LD, Sheehan JP Tags: J Neurosurg Source Type: research