Association between Modic changes and endplate sclerosis: Evidence from a clinical radiology study and a rabbit model

ConclusionSclerosis can occur in endplates with any type of MCs. However, the clinical and animal study suggests that sclerosis is greatest in endplates showing type III MCs.The translational potential of this articleThe study showed that sclerosis can occur in endplates with MCs type I, II and III. In patients with endplate sclerosis on plain radiographs or CT scans, the endplate can still represent an inflammatory process associated with chronic lower back pain.
Source: Journal of Orthopaedic Translation - Category: Orthopaedics Source Type: research