Aging impairs protective host defenses against Clostridioides (Clostridium) difficile infection in mice by suppressing neutrophil and IL-22 mediated immunity.

CONCLUSION: Increased susceptibility to C. difficile occurs in middle-aged mice modeling the community-acquired CDI demographics and is driven by an impaired innate immune response. PMID: 30099125 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30099125?dopt=Abstract

Source: Anaerobe - August 9, 2018 Category: Microbiology Authors: Peniche AG, Spinler JK, Boonma P, Savidge TC, Dann SM Tags: Anaerobe Source Type: research

More News: Clostridium Difficile | Epidemiology | Microbiology | Study | Translocation