Advantages of breast cancer visualization and characterization using synchrotron radiation phase-contrast tomography
The aim of this study was to highlight the advantages that propagation-based phase-contrast computed tomography (PB-CT) with synchrotron radiation can provide in breast cancer diagnostics. For the first time, a fresh and intact mastectomy sample from a 60 year old patient was scanned on the IMBL beamline at the Australian Synchrotron in PB-CT mode and reconstructed. The clinical picture was described and characterized by an experienced breast radiologist, who underlined the advantages of providing diagnosis on a PB-CT volume rather than conventional two-dimensional modalities. Subsequently, the image quality was assessed by 11 breast radiologists and medical imaging experts using a radiological scoring system. The results indicate that, with the radiation dose delivered to the sample being equal, the accuracy of a diagnosis made on PB-CT images is significantly higher than one using conventional techniques.
Source: Journal of Synchrotron Radiation - Category: Physics Authors: Pacil รจ , S. Baran, P. Dullin, C. Dimmock, M. Lockie, D. Missbach-Guntner, J. Quiney, H. McCormack, M. Mayo, S. Thompson, D. Nesterets, Y. Hall, C. Pavlov, K. Prodanovic, Z. Tonutti, M. Accardo, A. Fox, J. Tavakoli Taba, S. Lewis, S. Brennan, P. Hauserma Tags: phase-contrast breast CT synchrotron radiation breast cancer imaging research papers Source Type: research
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