Sex-Specific Association Between Nerve Growth Factor Polymorphism and Cardiac Vagal Modulation

Conclusions: The studied NGF polymorphism modulates autonomic outflow to the heart in a sex-dependent manner. The findings support the view that male T-allele carriers are at increased susceptibility for anxiety by association with low vagal activity and suggest a potential sex-specific genetic link between the highly comorbid anxiety disorders and cardiovascular diseases.
Source: Psychosomatic Medicine - Category: Psychiatry & Psychology Tags: Original Articles Source Type: research