High-risk breast cancer patients need cardiac monitoring

Some chemotherapy treatments for breast cancer increase a woman's risk of heart...Read more on AuntMinnie.comRelated Reading: ASTRO: Imaging, radiation oncology increasingly work as one Breast cancer patients aren't getting heart disease treatment CE-MRI predicts survival in breast cancer patients after chemo JNM: Cancer patients need cardiac review Trastuzumab + RT = no cardiac risk in breast cancer
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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Conclusion: This study showed that the 21-gene RS assay was not able to predict the benefit of PMRT for OS in women with T1-2 N1mic ER-positive HER2-negative breast cancer. However, further prospective larger sample-size trials are warranted to determine if a benefit exists. Introduction According to the latest Global Cancer Statistics 2018, breast cancer is still the most frequent cancer and the leading cause of cancer death among females worldwide (1). It is estimated that there will be about 2.1 million newly diagnosed female breast cancer cases and 627,000 cancer death in 2018 (1). The use of screening tests for ...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Authors: Sun D, Simon GJ, Skube S, Blaes AH, Melton GB, Zhang R Abstract Cardiotoxicity is a relatively common and particularly important adverse event caused by chemotherapy for breast cancer patients. Typical associative phenotypes, such as risk factors associated with diabetes, can often be detected solely based on the data elements existing in electronic health records; however, causal phenotypes, such as risk factors causing cardiotoxicity, require establishing causation between chemotherapy and determining new heart disease, and cannot be directly observedfrom EHR. We propose three phenotyping algorithms to a...
Source: AMIA Annual Symposium Proceedings - Category: Bioinformatics Tags: AMIA Annu Symp Proc Source Type: research
Lilly Rocha was 37 years old in 2008 when she began having strange symptoms. When people asked her questions, she knew the answers but couldn’t articulate them. A tingling sensation on her left breast became painful. She thought she might have breast cancer, but her doctor assured her she was just experiencing stress from her demanding job. Her symptoms continued to get worse, and doctors continued to dismiss her. Three months later, at work, she became seriously ill. Luckily, her boss recognized the symptoms—chest and jaw pain and numbness in her left hand—and drove her to the nearest emergency room, whe...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized heart health Source Type: news
In this study, we show that calorie restriction is protective against age-related increases in senescence and microglia activation and pro-inflammatory cytokine expression in an animal model of aging. Further, these protective effects mitigated age-related decline in neuroblast and neuronal production, and enhanced olfactory memory performance, a behavioral index of neurogenesis in the SVZ. Our results support the concept that calorie restriction might be an effective anti-aging intervention in the context of healthy brain aging. Greater Modest Activity in Late Life Correlates with Lower Incidence of Dementia ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
CONCLUSION: At 5 years after radiotherapy, median plasma BNP levels remained within the normal range, but the delta-BNP levels are directly related to the heart and ventricular dose received. PMID: 30431375 [PubMed - as supplied by publisher]
Source: International Journal of Radiation Biology - Category: Radiology Tags: Int J Radiat Biol Source Type: research
Women who receive chemotherapy for early-stage breast cancer are screened at baseline for underlying heart disease according to the treatment they are receiving, rather than their actual risk for heart failure.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
The objective of this work was to show how the influence of the microenvironment in tumor cells and consequently the onset and tumor progression is becoming increasingly more evident. Cancer is the second leading cause of death in the developed world, surpassed only by heart disease and obesity, and is increasingly recognised as an oncogenic factor in the genesis of this tumor. Inflammatory me- diators related to obesity are suspected to play a role in oncogenic modification of substrates metabolism of nutrients, most patients diagnosed with breast cancer underwent chemotherapy treatment, and this may be an aggravating fac...
Source: European Journal of Gynaecological Oncology - Category: OBGYN Tags: Eur J Gynaecol Oncol Source Type: research
(German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)) Many breast cancer therapies cause damage to the heart. However, in the largest study of its kind so far, scientists from the German Cancer Research Center (DKFZ) in Heidelberg have now shown that the risk of death from heart disease in breast cancer patients following radiotherapy or chemotherapy is no higher than it is among the average population. Good risk management in the hospitals as well as control screenings at short intervals seem to make up for elevated risks.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Journal of Cardiovascular Disease Research,2018,9,1,1-4.DOI:10.5530/jcdr.2018.1.1Published:March 2018Type:Review ArticleBreast Cancer and the Heart: Burden on the ChestAjit Singh,Hashir Kareem,Tom Devasia,Kanav Khera,Sheetal Chauhan,Yeswanth Rao K,andGanesh PAjit Singh*1, Hashir Kareem1, Tom Devasia1, Kanav Khera2, Sheetal Chauhan3, Yeswanth Rao K3, Ganesh P11Department of Cardiology, Kasturba Medical College and Hospital, Manipal Academy of Higher Education, Manipal, Karnataka, INDIA.2Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, INDIA...
Source: Journal of Cardiovascular Disease Research - Category: Cardiology Authors: Source Type: research
File this in the category of the stuff we should have been told but weren't. Many women diagnosed with breast cancer, are given chemotherapy as part of their treatment. One of the drugs commonly used is calledDoxorubicin, also known Adriamycin or Rubex, or as us patients have been known to call it'red devil', which carries a significant cardiac risk.When you are given it in chemo the nurses put on masks and special gowns to protect them. No thought of the patients. I was told it could cause some cardiac issues but now I am learning that the danger is very real and very concerning." “Both breast cancer and cardio...
Source: Caroline's Breast Cancer Blog - Category: Cancer & Oncology Tags: breast cancer treatment cardiac chemotherapy Source Type: blogs
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