Study elucidates epigenetic mechanisms behind autoimmune diseases

(Funda ç ã o de Amparo à Pesquisa do Estado de S ã o Paulo) Brazilian researchers use an editing tool to investigate a gene that plays a key role in eliminating autoaggressive cells and controlling the development of diseases such as type 1 diabetes. In tests with mice, the disrupting of medullary thymic epithelial cells gene impaired the processing of mRNA involved in their adhesion to autoaggressive T lymphocytes.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news