A novel real-space navigation paradigm reveals age- and gender-dependent changes of navigational strategies and hippocampal activation

ConclusionReal-space navigation testing was a feasible and sensitive method to depict age-related changes in navigation performance and strategy. Normalized error rates, total mean durations per item and total number of saccades were the most sensitive and practical parameters to indicate deterioration of allocentric navigation strategies and right hippocampal function in age irrespective of gender.
Source: Journal of Neurology - Category: Neurology Source Type: research