Additional Factors Regarding Clinical Outcomes of General Anesthesia and Conscious Sedation for Acute Ischemic Stroke

To the Editor Simonsen et al concluded that general anesthesia (GA) did not influence infarct growth compared with conscious sedation in endovascular-treated patients with acute stroke. This is an interesting study that addresses topical questions. However, we would like to point out some limitations.
Source: JAMA Neurology - Category: Neurology Source Type: research

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Publication date: Available online 12 December 2019Source: Anaesthesia &Intensive Care MedicineAuthor(s): Christopher J. TaylorAbstractIntracerebral haemorrhage (ICH) accounts for around 10–20% of all strokes and results from a variety of disorders. ICH is more likely to result in death or major disability than ischaemic stroke or subarachnoid haemorrhage. Rapid imaging allows early diagnosis and characterization of the localization and severity of the haemorrhage. Patients with significant acute ICH should be managed in a critical care unit. Treatment entails general supportive care, control of blood pressure an...
Source: Anaesthesia and intensive care medicine - Category: Anesthesiology Source Type: research
Conclusions: It was feasible to randomize AIS patients receiving either general anesthesia or conscious sedation for EVT.
Source: Journal of Neurosurgical Anesthesiology - Category: Anesthesiology Tags: Clinical Investigations Source Type: research
AbstractPurpose of reviewEndovascular thrombectomy (ET), the standard of treatment for emergent large vessel occlusion (ELVO) strokes, has been subject to rigorous efforts to further improve its usage and delivery for optimised patient outcomes. This review aims to provide an outline and discussion about the recently established and emerging recommendations regarding endovascular treatment of stroke.Recent findingsThe indications for ET have expanded continually, with perfusion imaging now enabling selection of patients presenting 6 –24 h after last-known-well, and improved device and operator proficiency allowi...
Source: Current Treatment Options in Cardiovascular Medicine - Category: Cardiology Source Type: research
ISCHEMIC stroke in children is very rare, with a reported incidence of 2 to 13 cases per 100,000 children.1 Tumors, endocarditis, vasculopathy, thrombotic disorders, and inflammatory disorders are the usual causes of an ischemic stroke in children.2,3 Transient cutaneous eruptions involving the extremities often precede the onset of neurologic symptoms in children with cardiac myxomas.4 Very few cases of ischemic stroke resulting from myxoma in children younger than 18 years have been reported in the literature.
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Case Report Source Type: research
ConclusionBaseline cut off thrombus appearance predicts a  higher number of thrombectomy maneuvers. In day to day practice this may prepare the neurointerventionalist for a more challenging endovascular procedure ahead. Stroke etiology, clinical outcomes and thrombus-specific characteristics did not show any associations with the thrombus appearance.
Source: Klinische Neuroradiologie - Category: Radiology Source Type: research
Introduction: Cerebral border zone infarctions (Watershed infarctions) on the early postoperative outcomes of patient undergoing carotid endarterectomy (CEA) were associated, in several studies, with a higher neurological complication rate. The current hypothesis is that hemodynamic phenomenon is involved. CEA performed under locoregional anesthesia enable to instantly reveal any hemodynamic phenomenon.
Source: European Journal of Vascular and Endovascular Surgery - Category: Surgery Authors: Source Type: research
This study aimed to assess the associations of pregnancy loss and risk of hypertension, type 2 diabetes (T2D), and hypercholesterolemia.
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Mother, Fetus, Neonate Source Type: research
Abstract Paediatric acute ischaemic stroke has a broad range of aetiologies and causes significant morbidity and mortality. Affected children have time urgent, critical needs that present unique challenges to the paediatrician, anaesthetist and to interventional radiologists. Diagnosis can often be delayed due to both the rarity of acute stroke in this patient cohort and also its diverse presentation, which is frequently non-specific. PMID: 31733159 [PubMed - as supplied by publisher]
Source: Paediatric Anaesthesia - Category: Anesthesiology Authors: Tags: Paediatr Anaesth Source Type: research
Janovák L, Dékány I, Farkas E, Bari F Abstract Stroke is an important cause of mortality and disability. Treatment options are limited, therefore the progress in this regard is urgently needed. Nimodipine, an L-type voltage-gated calcium channel antagonist dilates cerebral arterioles, but its systemic administration may cause potential side effects. We have previously constructed chitosan nanoparticles as drug carriers, which release nimodipine in response to decreasing pH typical of cerebral ischemia. Here we have set out to evaluate this nanomedical approach to deliver nimodipine selectivel...
Source: Neuropharmacology - Category: Drugs & Pharmacology Authors: Tags: Neuropharmacology Source Type: research
AbstractObjectiveTo evaluate the efficacy of electro-acupuncture (EA) or transcutaneous electrical acupoint stimulation (TEAS) on perioperative cerebral blood flow (CBF) and neurological function in ischemic stroke (IS) patients undergoing carotid artery stenting (CAS).MethodsIn total, 124 consecutive IS patients were randomly allocated to the EA, TEAS, and sham groups (groups A, T, and S; 41, 42, and 41 cases, respectively) by software-derived random-number sequence. Groups A and T received EA and TEAS, respectively, at the Shuigou (GV 26) and Baihui (GV 20), Hegu (LI4) and Waiguan (TE 5) acupoints. Group S received sham ...
Source: Chinese Journal of Integrative Medicine - Category: Internal Medicine Source Type: research
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