Supraventricular tachycardias, conduction disease and cardiomyopathy in three families with the same rare variant in TNNI3K (p.Glu768Lys)

Rare genetic variants in TNNI3K encoding Troponin-I interacting kinase have been linked to a distinct syndrome consisting primarily of supraventricular tachycardias and variably expressed conduction disturbance and dilated cardiomyopathy in two families.

Source: Heart Rhythm - July 15, 2018 Category: Cardiology Authors: Svitlana Podliesna, Julian Delanne, Lindsey Miller, David J. Tester, Merujan Uzunyan, Shoji Yano, Mischa Klerk, Bryan C. Cannon, Apichai Khongphatthanayothin, Gabriel Laurent, Geraldine Bertaux, Sylvie Falcon-Eicher, Shengnan Wu, Hai-Yun Yen, Hanlin Gao, Source Type: research