Multivitamins May Not Provide Heart Benefits

An analysis found no ties between multivitamins and the risk for cardiovascular disease, coronary heart disease or stroke incidence or mortality.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Vitamins Heart Source Type: news

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Publication date: September 2018Source: Clinica Chimica Acta, Volume 484Author(s): Gjin NdrepepaAbstractUric acid (UA) is an end product of purine metabolism in humans and great apes. UA acts as an antioxidant and it accounts for 50% of the total antioxidant capacity of biological fluids in humans. When present in cytoplasm of the cells or in acidic/hydrophobic milieu in atherosclerotic plaques, UA converts into a pro-oxidant agent and promotes oxidative stress and through this mechanism participates in the pathophysiology of human disease including cardiovascular disease (CVD). Most epidemiological studies but not all of ...
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
Conclusions: This result represents the first genetic evidence in a large cohort for the protective effect of PCSK9 inhibition on ischemic stroke and corroborates exploratory evidence from clinical trials. PCSK9 inhibition was not associated with variables other than those related to LDL (low-density lipoprotein) cholesterol, atherosclerosis, and type 2 diabetes mellitus, suggesting that other effects are either small or absent.
Source: Circulation: Cardiovascular Genetics - Category: Cardiology Authors: Tags: Cardiovascular Disease, Diabetes, Type 2, Genetic, Association Studies, Ischemic Stroke Original Articles Source Type: research
In conclusion, participating in sport clubs during adolescence might lead to a more pronounced risk-reduction for CHD mortality among men who also participate in sport activities during adulthood.
Source: Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Publication date: Available online 10 May 2018Source: Science &SportsAuthor(s): G. Kusuayi Mabele, C. Nkiama Ekisawa, C. Delecluse, F. Lepira Bompeka, A. NkodilaNatuhoyilaResumeContexteL’hypertension artérielle (HTA) est un facteur de risque cardiovasculaire majeur dans la survenue d’accidents vasculaires cérébraux, d’insuffisance cardiaque, d’insuffisance rénale et de maladies coronaires qui représentent les principales causes de décès dans le monde. Les données insuffisantes sur l’hypertension artérielle en milieu du travail ...
Source: Science and Sports - Category: Sports Medicine Source Type: research
Publication date: June 2017Source: Best Practice &Research Clinical Rheumatology, Volume 31, Issue 3Author(s): Sara Croca, Anisur RahmanAbstractCardiovascular disease (CVD), comprising coronary heart disease and stroke, is one of the most important causes of death in patients with systemic lupus erythematosus (SLE). The risks of developing both clinical CVD and sub-clinical atherosclerosis are increased in patients with SLE. This increase is not fully explained by traditional cardiovascular risk factors such as smoking, hypertension and elevated cholesterol, and it is believed that immune dysfunction also contributes t...
Source: Best Practice and Research Clinical Rheumatology - Category: Rheumatology Source Type: research
ConclusionsA diet featuring high food variety, high fish intake, and low sugar intake was negatively associated with the prevalence of cardiovascular outcomes among Inuit.
Source: Journal of the Academy of Nutrition and Dietetics - Category: Nutrition Source Type: research
Publication date: Available online 5 June 2018Source: The Lancet Diabetes &EndocrinologyAuthor(s): Mika Kivimäki, Jaana Pentti, Jane E Ferrie, G David Batty, Solja T Nyberg, Markus Jokela, Marianna Virtanen, Lars Alfredsson, Nico Dragano, Eleonor I Fransson, Marcel Goldberg, Anders Knutsson, Markku Koskenvuo, Aki Koskinen, Anne Kouvonen, Ritva Luukkonen, Tuula Oksanen, Reiner Rugulies, Johannes Siegrist, Archana Singh-ManouxSummaryBackgroundAlthough some cardiovascular disease prevention guidelines suggest a need to manage work stress in patients with established cardiometabolic disease, the evidence base for this...
Source: The Lancet Diabetes and Endocrinology - Category: Endocrinology Source Type: research
ConclusionsThere are large gaps in the use of proven medications for secondary prevention of cardiovascular disease in South America. Strategies to improve the sustained use of these medications will likely reduce cardiovascular disease burden substantially.
Source: Global Heart - Category: Cardiology Source Type: research
Conclusions: Our meta-analysis of clinical trials and prospective cohort studies demonstrates that MVM supplementation does not improve cardiovascular outcomes in the general population.
Source: Circulation: Cardiovascular Quality and Outcomes - Category: Cardiology Authors: Tags: Cardiovascular Disease, Diet and Nutrition, Meta Analysis, Quality and Outcomes, Cerebrovascular Disease/Stroke Original Articles Source Type: research
MONDAY, July 9, 2018 -- For postmenopausal African-American women, high-risk APOL1 genotype seems not to be associated with coronary heart disease, stroke, or mortality, according to a study published online July 3 in JAMA Cardiology. Nora...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
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