Cognitive Behavioral Therapy for antipsychotic-free schizophrenia spectrum disorders: Does therapy dose influence outcome?

This study investigated the effect of “dose” and the components of Cognitive Behavioral Therapy (CBT) on treatment effects. It is a secondary analysis of the ACTION (Assessment of Cognitive Therapy Instead of Neuroleptics) trial which investigated CBT for people with schizophrenia spectrum disorders that chose not to take antipsycho tic medication. Using instrumental variable methods, we found a “dose-response” such that each CBT session attended, reduced the primary outcome measure (the PANSS total score) by approximately 0.6 points (95% CI −1.20 to −0.06, p = 0.031).
Source: Schizophrenia Research - Category: Psychiatry Authors: Source Type: research

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Negative thoughts about psychotic experiences and fears of losing mental control may heighten the risk of suicide in patients with psychosis who were not taking antipsychotics, suggests areport inSchizophrenia Bulletin.“Overall, our findings emphasize the importance of clinicians promoting a recovery-focused and appropriately optimistic outlook when working with people with psychosis, taking care to avoid providing information that might heighten negative illness appraisals and/or fears of losing mental control, ” wrote Paul Hutton, Ph.D., of the Edinburgh Napier University in the United Kingdom and colleagues....
Source: Psychiatr News - Category: Psychiatry Tags: metacognition negative thoughts and beliefs Paul Hutton psychosis schizophrenia Schizophrenia Bulletin suicidal thinking suicidality suicide Source Type: research
Authors: Hesse K, Klingberg S Abstract Cognitive behavioral therapy (CBT) is an established treatment for the patients with psychosis including schizophrenia. The evidence for the efficacy of CBT is proved by randomized clinical trials and meta-analyses. Evidence-based treatment guidelines recommend CBT for routine treatment. The aim of this paper is to give a short practical guideline for different cognitive behavioral treatment strategies. Cognitive Behavior Therapy for psychosis (CBTp) is an adaptation of general principles of CBT modified for patients with psychotic disorders. Basis of CBT are cognitive models ...
Source: PPmP Psychotherapie Psychosomatik Medizinische Psychologie - Category: Psychiatry & Psychology Tags: Psychother Psychosom Med Psychol Source Type: research
This study improves our understanding of the neurobiology of treatment response and provides a foundation that will hopefully lead to greater precision and tailoring of the interventions offered to patients.
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
AbstractSeveral attributional biases have been discussed as putative causal factors in psychosis formation and maintenance. The monocausality bias in particular describes the excessive tendency to disregard multifactorial explanations and to instead attribute events to a single cause. To elucidate the role of monocausality in psychosis development, this study compared patients with an at-risk mental state of psychosis (ARMS,n = 49), first-episode patients (FEP,n = 35), chronic schizophrenia patients (SZ,n = 32) and healthy controls (HC,n = 39) on the Internal Personal...
Source: Cognitive Therapy and Research - Category: Psychiatry & Psychology Source Type: research
Authors: Guo ZH, Li ZJ, Ma Y, Sun J, Guo JH, Li WX, Wang ZQ, Xu HL, Ng RMK, Turkington D, Kingdon D PMID: 30221619 [PubMed - as supplied by publisher]
Source: The British Journal of Psychiatry for Mental Science - Category: Psychiatry Tags: Br J Psychiatry Source Type: research
Abstract Psychological treatments are increasingly regarded as useful interventions for schizophrenia. However, a comprehensive evaluation of the available evidence is lacking and the benefit of psychological interventions for patients with current positive symptoms is still debated. The present study aimed to evaluate the efficacy, acceptability and tolerability of psychological treatments for positive symptoms of schizophrenia by applying a network meta-analysis approach, that can integrate direct and indirect comparisons. We searched EMBASE, MEDLINE, PsycINFO, PubMed, BIOSIS, Cochrane Library, World Health Orga...
Source: World Psychiatry - Category: Psychiatry Authors: Tags: World Psychiatry Source Type: research
Suicide rates are high and have only been increasing over the years. Over 800,000 people die all over the world by suicide each year. A proportion of the suicides are murder suicides resulting in additional loss of life. Attempts at suicide occur more frequently and we have about one million suicide attempts occurring each year. Suicide is a heart-breaking problem that is growing and needs to be addressed in as many ways as is possible. Understanding the risk factors, knowing the warning signs and what to do about them, is a crucial step. The more the awareness the greater the impact on suicide prevention. Risk Factors f...
Source: Psych Central - Category: Psychiatry Authors: Tags: Depression General Suicide Source Type: news
This study was prospectively registered, number ISRCTN99672552. The trial is closed to accrual.FindingsFrom Jan 1, 2013, to May 31, 2015, we randomly assigned 487 participants to either CBT and treatment as usual (n=242) or treatment as usual alone (n=245). Analysis included 209 in the CBT group and 216 in the treatment as usual group. No difference occurred in the primary outcome (PANSS total at 21 months, mean difference −0·89, 95% CI −3·32 to 1·55; p=0·48), although the CBT group improved at the end of treatment (PANSS total at 9 months, mean difference −2·40, −...
Source: The Lancet Psychiatry - Category: Psychiatry Source Type: research
Authors: Tréhout M, Dollfus S Abstract Schizophrenia is a severe chronic mental disorder that mainly manifests by positive symptoms, negative symptoms, disorganized behavior and thought and cognitive impairments. Taken together, these symptoms have substantial impact on quality of life, well-being and functional outcome. Patients with schizophrenia have dramatically higher levels of cardiovascular and metabolic morbidity than the general population due to poor physical fitness and to sedentary lifestyle. They have a reduced life expectancy, and an excess mortality being two or three times more than that in t...
Source: L Encephale - Category: Psychiatry Tags: Encephale Source Type: research
CONCLUSIONS: Both interventions, in spite of some differences of efficacy, can be considered an important contribution to improve the patients' real-world functioning. Implications for rehabilitation Our study confirmed the need to include a set of psychosocial interventions for patients with schizophrenia spectrum disorders among usual treatment modalities. Techniques such as Befriending and Art therapy can be considered an important contribution to the treatment instruments required by the new community model for mental health. Befriending was found superior to Art therapy (between group effect) in improving psychosocial...
Source: Disability and Rehabilitation - Category: Rehabilitation Authors: Tags: Disabil Rehabil Source Type: research
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