The Brain Relaxation and Cerebral Metabolism in Stroke Volume Variation–directed Fluid Therapy During Supratentorial Tumors Resection: Crystalloid Solution Versus Colloid Solution

Background:Compared with goal-directed crystalloid therapy, goal-directed colloid therapy during high-risk surgery may improve postoperative outcome. Whether intraoperative fluid therapy based on goal-directed protocol with different types of fluid has distinctive effects on brain relaxation and cerebral metabolism during craniotomy remains unclear. Methods:Forty patients with supratentorial brain tumors undergoing craniotomy were randomly assigned to either a Ringer’s Lactate-based goal-directed group (LR group, n=20) or a 6% hydroxyethyl starch–based goal-directed group (HES group, n=20). The goal was achieved by maintaining a target stroke volume variation (SVV
Source: Journal of Neurosurgical Anesthesiology - Category: Anesthesiology Tags: Clinical Investigations Source Type: research