Association of single nucleotide polymorphisms in resistin gene with rheumatoid arthritis in a Chinese population

Journal of Clinical Laboratory Analysis, EarlyView.
Source: Journal of Clinical Laboratory Analysis - Category: Laboratory Medicine Authors: Source Type: research

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Publication date: October 2018Source: Biomedicine &Pharmacotherapy, Volume 106Author(s): Tao Xian, Yuyang Gan, Yi Lu, Mengxi Wang, Wanwan Yuan, Yumeng Zhou, Junye Chen, Kun Wang, Shaofeng Xiong, Qiren HuangAbstractIndomethacin (IDMT), a non-selective inhibitor of cycloxygenase-2 (COX-2), plays important roles in anti-inflammation and analgesia and it is commonly used to treat the patients with rheumatic and rheumatoid arthritis. Besides, various literatures reported that IDMT is a synthetic ligand of peroxisome proliferator activated receptor gamma (PPARγ). Rosiglitazone (RSG), an insulin-sensitizer, is also a sy...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
In the just posted issue of NIH MedlinePlus magazine, host of “American Ninja Warrior” and comedian Matt Iseman shares how he has coped with rheumatoid arthritis. From the relief he felt when he was diagnosed to the exercise and standup comedy that keep him going, Iseman is forthright about his challenges. He says, “I am walking proof…
Source: NLM In Focus - Category: Databases & Libraries Authors: Tags: Publications Source Type: blogs
We report a rare case of meningitis due to a combination ofStreptococcus mitis andNeisseria subflava. An 80-year-old female had a 4-year history of type II diabetes mellitus (DM) and an 11-year history of rheumatoid arthritis, which was treated with prednisolone, tacrolimus, and methotrexate. One month after the removal of a dental implant, she complained of a disturbance of consciousness and suffered a convulsion. A cerebrospinal fluid culture was found to be positive for bothS. mitis andN. subflava. After 14 days of antibiotic treatment with 4 g/day ceftriaxone, her stiff neck, somnolence, and laboratory data greatly imp...
Source: Case Reports in Neurology - Category: Neurology Source Type: research
Vladimira V. Boyadzieva, Nikolay Stoilov, Rumen M. Stoilov, Konstantin Tachkov, Maria Kamusheva, Konstantin Mitov, Guenka I. Petrova
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Marta Vomero, Cristiana Barbati, Tania Colasanti, Carlo Perricone, Lucia Novelli, Fulvia Ceccarelli, Francesca Romana Spinelli, Manuela Di Franco, Fabrizio Conti, Guido Valesini, Cristiano Alessandri
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
ConclusionsAssessment of comorbidities, psychological health and physical activity should be taken into account in order to address frequent RA-related severe fatigue.
Source: Joint Bone Spine - Category: Orthopaedics Source Type: research
In this study, 403 individuals with newly diagnosed and untreated RA were consecutively recruited. We calculated the Disease Activity Score assessed using 28-joint counts for swelling and tenderness (DAS28). Levels of serum RBP4, interleukin-6 (IL-6) and tumor necrosis factor (TNF) α were tested. IR was defined as Homeostasis model assessment for insulin resistance (HOMA-IR) index greater than or equal 2.40.ResultsIn those 403 patients, 68 (16.9%) were male and the median age was 43 years (IQR, 36–52). There was an evidently positive correlation between increased serum levels of RBP4 and increasing severity of ...
Source: Joint Bone Spine - Category: Orthopaedics Source Type: research
Publication date: Available online 17 July 2018Source: Joint Bone SpineAuthor(s): Françoise Fayet, Carine Savel, Malory Rodere, Martin Soubrier, Sylvain Mathieu
Source: Joint Bone Spine - Category: Orthopaedics Source Type: research
Publication date: Available online 17 July 2018Source: Joint Bone SpineAuthor(s): Gaëlle Clavel, Johanna Sigaux, Luca Semerano
Source: Joint Bone Spine - Category: Orthopaedics Source Type: research
Publication date: Available online 17 July 2018Source: Autoimmunity ReviewsAuthor(s): Aram Musaelyan, Sergey Lapin, Vladimir Nazarov, Olga Tkachenko, Boris Gilburd, Alexandra Mazing, Lilia Mikhailova, Yehuda ShoenfeldAbstractVimentin is a protein of intermediate filament family, which is expressed in all mesenchymal cells. Vimentin plays a key role in the physiology of the cell, cellular interactions and the functioning of the immune system. Post-translationally modified and native forms of vimentin are involved in the pathogenesis of inflammation and many autoimmune diseases: rheumatoid arthritis, sarcoidosis, systemic lu...
Source: Autoimmunity Reviews - Category: Allergy & Immunology Source Type: research
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