Optimization of Drugs Pharmacotherapy during Pregnancy Using Physiologically Based Pharmacokinetic Models - An Update.

CONCLUSION: More work is needed to fill the gaps in knowledge needed to more accurately and mechanistically simulate simultaneous exposure of the pregnant mother and her fetus/ embryo to drugs using pregnancy physiologically-based pharmacokinetic modeling approach. PMID: 29962340 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29962340?dopt=Abstract

Source: Current Drug Metabolism - July 1, 2018 Category: Drugs & Pharmacology Authors: Idkaidek N, Alsmadi MM Tags: Curr Drug Metab Source Type: research