EGFR inhibition by anti‐CD147 therapy in Cutaneous Squamous cell Carcinoma

Conclusions: Inhibition and down‐regulation of CD147 in cSCC resulted in suppression of the malignant phenotype in vitro and in vivo which may be mediated in part by an alteration in EGFR expression. As a result, CD147 may serve as a potential therapeutic target for advanced cSCC. Head Neck, 2014

Source: Head and Neck - October 1, 2014 Category: ENT & OMF Authors: John W. Frederick, Larissa Sweeny, Yolanda Hartman, Tong Zhou, Eben L. Rosenthal Tags: Original Article Source Type: research