RNA sequencing reveals target genes of temporomandibular joint osteoarthritis in rats after the treatment of low-intensity pulsed ultrasound.

CONCLUSION: This study reveals the potential therapeutic genes related to TMJ-OA. Especially the circadian Per-2 gene was detected up-regulated by the treatment of LIPUS. It provides us a precious, new target OA-related gene and further investigation of gene-function will provide us new insights in understanding the potential mechanical underling TMJ-OA.
PMID: 29885465 [PubMed - as supplied by publisher]

Source: Gene - June 6, 2018 Category: Genetics & Stem Cells Authors: He D, An Y, Li Y, Wang J, Wu G, Chen L, Zhu G Tags: Gene Source Type: research