Enhanced Coronary Arteriolar Contraction to Vasopressin in Patients with Diabetes after Cardiac Surgery

Cardioplegic arrest (CP) and cardiopulmonary bypass (CPB) are associated with vasomotor dysfunction of coronary arterioles in diabetic patients undergoing cardiac surgery. We hypothesized that diabetes may up-regulate vasopressin receptor expression and alter the contractile response of coronary arterioles to vasopressin in the setting of CP/CPB.

Source: The Journal of Thoracic and Cardiovascular Surgery - June 8, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Nicholas Sellke, Alex Kuczmarski, Isabella Lawandy, Victoria L. Cole, Afshin Ehsan, Arun K. Singh, Yuhong Liu, Frank W. Sellke, Jun Feng Source Type: research