Acrodermatitis dysmetabolica in phenylketonuria

A 17-month-old girl with a history of phenylketonuria (PKU) and chronic kidney disease (CKD) secondary to unilateral renal agenesis presented with failure to thrive, diarrhea, and an extensive skin rash. Her parents reported increased irritability, decreased oral intake, and a gradually worsening rash over the last 14 days, with watery diarrhea present for 3 days. The patient was on a special amino-acid-restricted diet formula since birth for PKU and CKD. On examination, a diffuse erythematous confluent rash was present in the perioral region and the inguinal and perianal areas (as shown in Figs.
Source: Pediatrics and Neonatology - Category: Perinatology & Neonatology Authors: Tags: Images Source Type: research