In-house automated synthesis of L-[11C]Glutamine with the use of a siemens H11CN Box.

Conclusions: A method for the automated production of L-[11C]glutamine was achieved with the use of an in-house module attached to a Siemens H11CN module. Specificity and reactivity of the produced L-[11C]glutamine was validated in vitro using a glioblastoma cell line. This provides a platform for consistent-routine production of L-[11C]glutamine which can be used as a potential PET imaging agent. References: [1] L. Zhu, et. al. J. Nucl. Med. 2017, 58, 533-537.

Source: Journal of Nuclear Medicine - May 23, 2018 Category: Nuclear Medicine Authors: Joseph, S., Sattiraju, A., Oya, S., Jurewicz, A., Castrillon, J., Soffing, M., Mintz, A., Carberry, P. Tags: Tech Papers V: Professional Practices & amp; Educational Exhibits and Radiopharmaceutical Science, Biology amp; Dosimetry Technologist Abstracts Source Type: research