Hypoxic preconditioning reduces propofol-induced neuroapoptosis via regulation of Bcl-2 and Bax and downregulation of activated caspase-3 in the hippocampus of neonatal rats.

Conclusion: Our results indicate that pretreatment with hypoxic preconditioning prevents propofol-induced neuroapoptosis by increasing the levels of Bcl-2 and decreasing the levels of Bax and cleaved-caspase-3. PMID: 29790425 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29790425?dopt=Abstract

Source: Neurological Research - May 26, 2018 Category: Neurology Tags: Neurol Res Source Type: research