A Twenty-Year Retrospective Diagnosis of Congenital Cytomegalovirus Infection

Approximately 85-90% of infants with congenital cytomegalovirus infection (CCMVI) are asymptomatic at birth. Among them, however, approximately 10% develop sequelae, such as sensorineural hearing impairment, epilepsy, and cerebral palsy.1,2 A definite diagnosis of CCMVI is made by detecting CMV or its genome in clinical specimens obtained within three weeks after birth,3 because subsequent virus detection may represent acquired infection. Such a strict time constraint in addition to the nonspecific clinical features makes late-onset CCMVI extremely difficult to diagnose.
Source: Pediatric Neurology - Category: Neurology Authors: Tags: Short Communication Source Type: research