Targeting energy metabolism via the mitochondrial pyruvate carrier as a novel approach to attenuate neurodegeneration

Several molecular pathways are currently being targeted in attempts to develop disease-modifying therapies to slow down neurodegeneration in Parkinson ’s disease. Failure of cellular energy metabolism has long ...

Source: Molecular Neurodegeneration - May 24, 2018 Category: Neurology Authors: Emmanuel Quansah, Wouter Peelaerts, J. William Langston, David K. Simon, Jerry Colca and Patrik Brundin Tags: Review Source Type: research