DNAJA4 Deficiency Enhances NF-kappa B-related Growth Arrest Induced by Hyperthermia in Human Keratinocytes
Exogeneous hyperthermia, defined as a 30 –60 minute exposure to a thermal stimulus of 40–44 °C, has been employed in treatment of an array of diseases [1]. This technique has proved effective in the treatment of various of cancers such as cervical, bladder and head and neck cancer [2–4]. Within our clinic we have used local hype rthermia at 44 ± 0.1 °C in the treatment of plantar warts and found this procedure to be more effective than that of conventional therapies [5,6]. With this method, we have also successfully alleviated cutaneous warts in patients with diabetes mellitus [7], systemic lupus erythematosus (SLE) [8], Darier disease [9] and pregnancy [10], all of which had experienced failures with conventional treatments.
Source: Journal of Dermatological Science - Category: Dermatology Authors: Yu-Zhe Sun, Yi Ren, Yu-Jing Zhang, Yang Han, Yang Yang, Ya-Li Gao, Li-Li Zhu, Rui-Qun Qi, Hong-Duo Chen, Xing-Hua Gao Source Type: research
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