Paediatric sarcoidosis

Sarcoidosis, also called Besnier-Boeck-Schaumann disease, was first described in the 19th century as a systemic granulomatous disorder involving predominantly the lungs and the lymphatic system [1]. More than a century after, its pathogenesis remains unknown and its pathophysiology remains controversial [2,3]. The current hypothesis is a multifactorial disease associating a genetic susceptibility and an environmental exposure that triggers or enhances the inflammatory and granulomatous process. Sarcoidosis is mainly an adult disease, children being affected around 10 times less frequently.

Source: Paediatric Respiratory Reviews - May 18, 2018 Category: Respiratory Medicine Authors: Nadia Nathan, Chiara Sileo, Alain Calender, Yves Pacheco, Dominique Valeyre, Annick Clement, for the French Sarcoidosis Group (GSF), the Silicosis Group Tags: Review Source Type: research