High Disease Activity Is Associated with Self-reported Depression and Predicts Persistent Depression in Early Rheumatoid Arthritis: Results from the Ontario Best Practices Research Initiative.

CONCLUSION: Depression in ERA is common and initial high disease activity is associated with the probability of depression and its persistence. This risk seems particularly modified in women with active disease and represents an area for targeted focus and screening. Future studies in ERA are needed to determine if intervening during the "window of opportunity" to control disease activity has the potential to mitigate the development and maintenance of adverse mental health outcomes, including depression. PMID: 29764967 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29764967?dopt=Abstract

Source: J Rheumatol - May 15, 2018 Category: Rheumatology Authors: Kuriya B, Joshi R, Movahedi M, Rampakakis E, Sampalis JS, Bombardier C, Ontario Best Practices Research Initiative Investigators Tags: J Rheumatol Source Type: research