Survival Outcomes of Men with Lymph Node-positive Prostate Cancer After Radical Prostatectomy: A Comparative Analysis of Different Postoperative Management Strategies

Conclusions In men with LNM after RP, ADT+EBRT improved survival over either observation or adjuvant ADT alone. This survival benefit increases with higher-risk disease. Patient summary Lymph node metastasis following radical prostatectomy is associated with poor survival outcomes. However, we found that adjuvant androgen deprivation therapy with external beam radiation therapy improved survival in these patients. Lymph node metastasis following radical prostatectomy is associated with poor survival outcomes. Adjuvant androgen deprivation therapy with external beam radiation therapy confers a long-term overall survival advantage than either observation or androgen deprivation therapy alone.
Source: European Urology - Category: Urology & Nephrology Source Type: research