Heat-targeted drug delivery: A promising approach for organsparing treatment of bladder cancer.THERMODOX ®.

Heat-targeted drug delivery: A promising approach for organsparing treatment of bladder cancer.THERMODOX®. Arch Esp Urol. 2018 May;71(4):447-452 Authors: Aminsharifi A, Brousell SC, Chang A, León J, Inman BA Abstract Disease recurrence and progression remain as significant challenges for the management of non-muscle invasive bladder cancer (NMIBC). In recent years, novel drugs and delivery systems have been investigated as strategies to reduce recurrence, progression and mortality. In this review, we focus on the role of intravesical hyperthermic chemotherapy and discuss a novel approach involving a heat-activated drug delivery system (ThermoDox®) that enables local accumulation of systemic chemotherapy. PMID: 29745934 [PubMed - in process]
Source: Archivos Espanoles de Urologia - Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research