Prognostic and clinical significance of histone deacetylase 1 expression in breast cancer: A meta-analysis

Conclusion Overall, our meta-analysis demonstrated an association between increased HDAC1 expression and better OS in Asian breast cancer patients. In addition, HDAC1 over-expression correlated with positive ER and negative HER2 expression in breast cancer. However, researches in large patients' randomised controlled trials (RCTs) are needed to confirm the results.
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research