Drinking more water does not slow decline of kidney function for kidney disease patients

(Lawson Health Research Institute) A new study, published in JAMA by researchers at Lawson Health Research Institute and Western University, found that coaching patients with chronic kidney disease (CKD) to drink more water does not slow down the decline of their kidney function.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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This study aimed to investigate the incidence of atrial fibrillation (AF) and its prognosis in the patients after dialysis initiation. METHODS: A total of 1524 patients with chronic kidney disease who were initiated on dialysis were included. Dialysis was initiated between October 2011 and September 2013. Electrocardiogram was obtained at dialysis initiation, in March 2015, and September 2016. The mortality and cardiovascular disease (CVD) event rates of 1520 patients (1028 men and 492 women; mean age, 67.5 ± 13.1 years) who were followed up were compared, and they were divided into 2 groups: the AF group (...
Source: Acta Cardiologica - Category: Cardiology Tags: Acta Cardiol Source Type: research
ConclusionsOur results provide evidence that PROMIS-57 and PROMIS-29 are highly reliable and valid instruments among kidney transplant recipients. We propose it as a valuable tool to assess important domains of the illness experience.
Source: Quality of Life Research - Category: Health Management Source Type: research
Conclusions: Our data indicate that higher TSH concentrations are positively correlated with CKD prevalence and that  a high TSH concentration is a risk factor for CKD development.Nephron
Source: Nephron - Category: Urology & Nephrology Source Type: research
Publication date: Available online 21 February 2019Source: American Journal of Kidney DiseasesAuthor(s): Vimal K. Derebail, Emily J. Ciccone, Qingning Zhou, R. Rosina Kilgore, Jianwen Cai, Kenneth I. AtagaRationale &ObjectiveProgression of chronic kidney disease (CKD) in sickle cell disease (SCD) and its risk factors remain poorly defined. We identified characteristics associated with CKD as well as decline in estimated glomerular filtration rate (eGFR) and presence of proteinuria over time in adults with SCD.Study DesignRetrospective observational study.Setting &ParticipantsPatients with SCD 18 years or older in a...
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
ConclusionsCKD stage 3 was not associated with an increase in fracture status. QUS parameters were similarly associated with fracture status in patients with and without CKD.
Source: Osteoporosis International - Category: Orthopaedics Source Type: research
This study comprised 2,516 hypertensive patients who had had at least two serum creatinine measurements over a four-year period. An eGFR reduction of ≥10% per year has been deemed as high-eGFR and a reduction in eGFR of less than 10% per year as a low decline. The end-points were: coronary artery disease, stroke, transitory ischemic accident, peripheral arterial disease, heart failure, atrial fibrillation, death from any cause. Cox regression analyses adjusted for potentially confounding factors were conducted. RESULTS: 2,354 patients with low rate of eGFR decline and 149 with high-rate of eGFR decline were analyze...
Source: American Journal of Hypertension - Category: Cardiology Authors: Tags: Am J Hypertens Source Type: research
The prevalence of non-communicable diseases is increasing worldwide, which coincides with the persistence of infectious diseases including tuberculosis. These can synergistically affect individual and population health. Three non-communicable diseases that are relevant because of their associated morbidity, mortality and disability are type 2 diabetes mellitus, chronic kidney disease and rheumatoid arthritis. There is some evidence that patients with these conditions are at increased risk of acquiring latent tuberculosis infection (LTBI) and of this progressing to active disease.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
Cardiovascular disease (CVD) remains a leading cause of mortality in chronic kidney disease (CKD) patients. Interventions targeting traditional risk factors have largely proven ineffective in CKD patients in part because of the increased role of nontraditional risk factors such as chronic inflammation. Omega-3 fatty acids ( ω3FA) are inexpensive and safe natural agents, which target inflammation and have potential cardioprotective benefits. The aim of the study was to determine the effects of ω3FA supplementation upon serum interleukin (IL)-12, IL-18, and highly sensitive C-reactive protein (hsCRP) in patients with S tage 3-4 CKD.
Source: Journal of Renal Nutrition - Category: Urology & Nephrology Authors: Tags: Original Research Source Type: research
DISCUSSION: Physical activity, diet, body mass index, the presence of diabetes, and the presence of chronic kidney disease were strong risk factors for hypertension. Many of these risk factors are modifiable and highlight targets for future prevention strategies. PMID: 30785634 [PubMed - in process]
Source: Health Reports - Category: International Medicine & Public Health Tags: Health Rep Source Type: research
Circulating C3 has been associated with diabetes and hypertension, which are the leading causes of chronic kidney disease (CKD). C3 activation is considered to contribute to several renal diseases. Here we exa...
Source: BMC Nephrology - Category: Urology & Nephrology Authors: Tags: Research article Source Type: research
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