Medical and Semi-surgical Treatments for Fuchs Endothelial Corneal Dystrophy.

Medical and Semi-surgical Treatments for Fuchs Endothelial Corneal Dystrophy. Klin Monbl Augenheilkd. 2018 May 03;: Authors: Wacker K, Baratz KH, Fautsch MP, Patel SV Abstract Unraveling the genetic mechanisms of Fuchs endothelial corneal dystrophy has opened new possibilities for future targeted medical therapy of the disease. Until these possibilities mature, regenerative semi-surgical approaches by cell injection or cell sheet transfer could help expand the donor pool, and possibly enable autologous transplantation. Descemet membrane stripping alone and acellular Descemet membrane transfer are more immediate surgical approaches that could be temporary treatments in some patients, though there is a lack of understanding of the factors that predict success for these procedures. Regardless of approach, clinical trials will be necessary, and clinicians should therefore try to standardize their methods of assessing disease severity and the outcomes of intervention. PMID: 29723889 [PubMed - as supplied by publisher]
Source: Klinische Monatsblatter fur Augenheilkunde - Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research