Aberrant Cortical Integration in First-Episode Psychosis During Natural Audiovisual Processing

Functional magnetic resonance imaging (fMRI) studies of psychotic disorders have reported both hypo- and hyperactivity in numerous brain regions. In line with the dysconnection hypothesis, these regions include cortical integrative hub regions. However, most earlier studies have focused on a single cognitive function at a time, assessed by delivering artificial stimuli to chronic patients. Thus, it remains unresolved whether these findings are present already in early psychosis and whether they translate to real-life-like conditions which require multisensory processing and integration.
Source: Biological Psychiatry - Category: Psychiatry Authors: Tags: Archival Report Source Type: research