Treatment of cystoid macular edema secondary to retinitis pigmentosa: a systematic review

There are various treatments for cystoid macular edema (CME) secondary to retinitis pigmentosa; however, the evidence for these treatments has not been previously systematically reviewed. Our review that includes 23 studies shows that oral carbonic anhydrase inhibitors (including acetazolamide and methazolamide) and topical carbonic anhydrase inhibitors (dorzolamide and brinzolamide) are effective first-line treatments. In patients unresponsive to carbonic anhydrase inhibitor treatment, intravitreal steroids (triamcinolone acetonide and sustained-release dexamethasone implants), oral corticosteroid (deflazacort), intravitreal antivascular endothelial growth factor agents (ranibizumab and bevacizumab), grid  laser photocoagulation, pars plana vitrectomy, or ketorolac were also effective in improving CME secondary to retinitis pigmentosa.

Source: Survey of Ophthalmology - October 5, 2017 Category: Opthalmology Authors: Malini Bakthavatchalam, Frank H.P. Lai, Shi Song Rong, Danny S. Ng, Marten E. Brelen Tags: Major review Source Type: research