Nonlinear Inverted-U Shaped Relationship between Aging and Epidermal Innervation in the Rat Plantar Hind Paw: a Laser Scanning Confocal Microscopy Study

• Laser-scanning microscopy is used for quantification of rat epidermal nerves• Advanced age is associated with decreased density of epidermal nerves• Middle-aged rats have increased epidermal nerves.• An inverted-U shaped relationship between aging and epidermal nerve density• Epidermal n erve density is not correlated with paw withdrawal thresholds
Source: The Journal of Pain - Category: Materials Science Authors: Tags: Original Report Source Type: research