Novel pathway identified in development of acute myeloid leukemia with poor prognosis

(National University of Singapore, Yong Loo Lin School of Medicine) NUS researchers have discovered a new pathway by which a severe form of acute myeloid leukemia (AML) develops. The main player in the pathway, a protein called SHARP1, promotes leukemia development and maintenance, both on its own and through its actions on other genes. The discovery could lead to the development of novel SHARP1-specific treatments for this difficult-to-treat form of AML.
Source: EurekAlert! - Biology - Category: Biology Source Type: news