439 The role of IL-37 in psoriasis

This study aimed to test the hypothesis that IL-37 suppresses inflammation in psoriasis. Biopsies from human lesional psoriasis (LP) and non-lesional psoriasis (NLP) were collected. In addition, biopsies were collected during treatment with either adalimumab (n= 6) or ustekinumab (n= 12; 6 responders and 6 non-responders).

Source: Journal of Investigative Dermatology - April 19, 2018 Category: Dermatology Authors: K. R ønholt, A. Langkilde, C. Johansen, R. Vales, C. Dinarello, L. Iversen Tags: Clinical Research: Pathophysiology and Therapeutics Source Type: research