719 Abnormalities in skin barrier status correlate with autism in a murine model: Could assessments of skin barrier function assist in early diagnosis of autism?

Autism spectrum disorders (ASD), which are characterized by deficits in sociability and communication, affect as many as 1 in 68 children worldwide. Recent epidemiological studies suggest a significant statistical correlation between ASD and atopic dermatitis (AD), asthma, eczema, and food intolerance. Currently, the diagnosis of ASD is based primarily on altered behavior, changes that become apparent only after 2 years. Because an early diagnosis could improve disease outcomes in ASD, significant efforts are underway to develop new diagnostic methods.

Source: Journal of Investigative Dermatology - April 19, 2018 Category: Dermatology Authors: K. Shin, S. Jeong, H. Kim, B. Park, D. Crumrine, Y. Uchida, K. Park, P. Elias Tags: Epidermal Structure and Barrier Function Source Type: research