Diagnostic and Treatment Challenges of Sighted Non –24-Hour Sleep-Wake Disorder

Conclusions:N24SWD is a chronic debilitating disorder that is often overlooked in sighted people and can be challenging to diagnose and treat. Tools to assess circadian pattern and timing can be effectively applied to aid the diagnosis. The progressive delay of the circadian rhythm poses a challenge for determining the most effective timing for melatonin and bright light therapies. Furthermore, once the circadian sleep-wake rhythm is entrained, long-term effectiveness is limited because of the behavioral and environmental structure that is required to maintain stable entrainment.Citation:Malkani RG, Abbott SM, Reid KJ, Zee PC. Diagnostic and treatment challenges of sighted non–24-hour sleep-wake disorder.J Clin Sleep Med. 2018;14(4):603–613.
Source: Journal of Clinical Sleep Medicine : JCSM - Category: Sleep Medicine Source Type: research